Recent studies have linked the type 2 diabetes medication Invokana to cardiovascular side effects including blood clots that could lead to a heart attack.
Free Invokana Class Action Lawsuit Evaluation: If you or a loved one was injured by Invokana, you should contact our law firm immediately. You may be entitled to compensation by filing a suit against the manufacturer and our lawyers can help.
FDA Warning on Invokana
A heart attack, or myocardial infarction (MI), is a potential side effect of Invokana (generic: canagliflozin). The condition can damage cells inside the heart and lead to permanent damage and even death.
In May 2015, the U.S. Food & Drug Administration (FDA) warned that Invokana users may be at an increased risk of developing severe cardiovascular complications stemming from diabetic ketoacidosis (DKA) when insulin levels are too low. If left untreated, DKA can lead to heart failure and other cardiac side effects.
Warning signs of a heart attack may include:
- Chest pain
- Shortness of breath
- Nausea / vomiting
- Heartburn / indigestion
- Arm pain
- Upper back pain
- No symptoms (approximately 25% of all heart attacks are ‘silent,’ without chest pain or new symptoms. Silent heart attacks are especially common among patients with type 2 diabetes)
If you think you may be having a heart attack, do not drive to the hospital unless you have no other option. Ambulance personnel can start treatment as soon as they arrive. If you are not allergic to aspirin and do not have a history of internal bleeding, emergency response may ask you to chew one 325mg aspirin slowly.
Once at the hospital, an emergency department doctor will examine you and run tests to see if your chest pain stems from a heart attack or another cause. Tests may include an electrocardiogram (ECG), chest X-ray and/or blood tests.
Risk of Heart Problems with Invokana Known Before Approval
Before Invokana was even approved, red flags were raised about the medication’s potential to cause heart problems. A review of information considered by the FDA’s Endocrinologic and Metabolic Drug Advisory Committee in Jan. 2013 suggested that Invokana may be associated with an increased risk of major adverse cardiovascular events (MACE+) including heart attacks and strokes.
In one pre-approval clinical trial, there were 13 cardiovascular events in patients treated with Invokana, while there was only 1 in the placebo group. In an 8 to 7 vote, committee members expressed concerns about excluding signs of a high risk margin for Invokana heart problems. Most of the advisory committee “expressed some level of concern over the increased stroke incidence, low-density cholesterol, and MACE+ events at thirty days, but described a general comfort with the data overall,” according to the minutes from the meeting. “These committee members generally discussed a need for a longer period of exposure, particularly for a drug that treats a chronic disease.”
The panel ultimately voted 10 to 5 to recommend approval of Invokana for the treatment of type 2 diabetes. While the advisory committee’s recommendations are not binding, FDA often follows the advice and Invokana was approved for use in the U.S. a short time later.
Do I Have an Invokana Heart Attack Lawsuit?
The Class Action Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Invokana lawsuits. We are handling individual litigation nationwide and currently accepting new heart attack cases in all 50 states.
Free Confidential Case Evaluation: Again, if you had a heart attack after taking Invokana, you should contact our law firm immediately. You may be entitled to compensation by filing a lawsuit and our we can help.