What is Proquin XR?
Proquin XR (ciprofloxacin) is a fluoroquinolone antibiotic medication used to treat simple bladder infections caused by bacteria. The drug works by entering the bacterial cells and inhibiting an enzyme involved in replicating and replacing the genetic material (DNA) of the bacteria.
FDA ‘Black Box’ Warning on Tendinitis, Tendon Ruptures
In July 2008, the U.S. Food & Drug Administration (FDA) required that the labeling of fluoroquinolone antibiotics carry a ‘black box’ warning alerting patients to a potential risk of tendon ruptures and tendonitis (tendinitis). The warning indicates that these risks are increased in patients over the age of 60, in organ transplant recipients, and when fluoroquinolones are taken with concomitant steroid therapy. FDA also required manufacturers to provide a Medication Guideline (PDF) highlighting these potential side effects.
Antibiotic Nerve Damage
In 2013, FDA required that fluoroquinolone labels be again updated, this time with warnings about a potential risk for nerve damage associated with the medications. The agency enforced the warnings after reviewing dozens of adverse event reports describing peripheral neuropathy in patients treated with the drugs. FDA concluded that the “potential rapid onset and permanence” of neuropathy was not adequately described in the drugs’ earlier labeling, and required that statements describing this side effect as “rare” be removed. The agency advised patients with symptoms of the condition to contact their doctor immediately.
Peripheral Neuropathy Symptoms
According to the Mayo Clinic, signs and symptoms of peripheral neuropathy may include:
- Gradual onset of numbness and tingling in your feet or hands, which may spread upward into your legs and arms
- Sharp, jabbing or burning pain
- Extreme sensitivity to touch
- Lack of coordination and falling
- Muscle weakness or paralysis if motor nerves are affected
If neuropathy affects autonomic nerves, symptoms may include:
- Heat intolerance and altered sweating
- Bowel, bladder or digestive problems
- Changes in blood pressure, causing dizziness or lightheadedness
Proquin XR Aortic Aneurysm
New research has also linked fluoroquinolone antibiotics like Proquin to life-threatening aortic complications. A study published in JAMA Internal Medicine in October 2015 found that fluoroquinolone use may increase the risk of aortic aneurysm and aortic dissection, both of which can cause death from internal bleeding.
For the study, researchers at National Taiwan University’s Department of Emergency Medicine looked at 1,477 patients who had been hospitalized for aortic aneurysm or dissection, and compared them against a control group of 147,700 patients who had not been hospitalized. The findings suggested that current fluoroquinolone use increased the risk of aortic aneurysm by more than double. Past use increased the risk by nearly 50%.
“Use of fluoroquinolones was associated with an increased risk of aortic aneurysm and dissection,” the researchers concluded. “While these were rare events, physicians should be aware of this possible drug safety risk associated with fluoroquinolone therapy.”
What is an Aortic Aneurysm?
An aortic aneurysm occurs when a bulge develops in the wall of the aorta, the largest artery in the human body. The medical literature lists two main types of aortic aneurysm:
- Thoracic Aortic Aneurysm (TAA) – Occurs in the part of the aorta running through the chest. Symptoms include: pain in the jaw, neck, back or chest; coughing / hoarseness; shortness of breath, and trouble breathing or swallowing.
- Abdominal Aortic aneurysm (AAA) – Occurs in the part of the aorta that runs through the abdomen. Symptoms include: throbbing feeling in the abdomen; deep pain in the back or side of the abdomen, and a steady, gnawing pain in the abdomen that lasts for hours or days.
Proquin Side Effects
- Nerve damage
- Peripheral neuropathy
- Aortic Aneurysm
- Muscle weakness
- Tendon ruptures
- Central nervous system disorders
- Hypersensitivity reactions
- Loss of consciousness
- Cardiovascular collapse
- Life-threatening skin reactions
- Toxic epidermal necrolysis (TEN)
- Stevens-Johnson syndrome (SJS)
- Clostridium difficile associated diarrhea
Has a Class Action Been Filed?
Although Schmidt & Clark, LLP, is a nationally recognized class action firm, we have decided against the filing of a Proquin class action lawsuit, and are instead accepting potential individual claims on behalf of injured parties. Class actions can have major disadvantages to plaintiffs including higher attorneys’ fees and “low-ball” settlement offers. Our lawyers file individual lawsuits because we believe personal legal representation is the best way to help people who were injured by allegedly defective drugs like Proquin XR. If we determine that you have a valid claim, you may be eligible to receive compensation for medical expenses, lost wages, pain and suffering, and other damages.
Do I Have a Proquin XR Lawsuit?
The Class Action Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Proquin lawsuits. We are handling individual litigation nationwide and currently investigating potential settlements in all 50 states.
Free Confidential Case Evaluation: Again, if you were injured by Proquin side effects, you should contact our law firm immediately. You may be entitled to a settlement by filing a suit and we can help.