Noroxin is a fluoroquinolone antibiotic drug used to treat urinary tract infections, certain sexually transmitted diseases and prostatitis. The Japanese pharmaceutical manufacturer Kyorin Seiyaku K.K. (Kyorin) patented norfloxacin (the active ingredient in Noroxin) in 1979 and subsequently licensed it to Merck & Co. The U.S. Food & Drug Administration (FDA) approved Noroxin in 1986, and it comes in the form of oral tablets, injectable solutions and topical formulations applied to the ears and eyes.
Noroxin Side Effects
Fluoroquinolone antibiotic medications like Noroxin have been linked to the following serious side effects:
- Peripheral neuropathy
- Aortic aneurism
- Aortic dissection
- Collagen disorders
- Muscle weakness (myasthenia gravis)
- Tendon ruptures
- Central nervous system disorders (tremors, restlessness, lightheadedness and confusion)
- Hypersensitivity reactions (loss of consciousness, cardiovascular collapse)
- Cardiovascular collapse
- Life-threatening skin reactions
- Toxic epidermal necrolysis (TEN)
- Stevens-Johnson syndrome (SJS)
- Clostridium difficile associated diarrhea (diarrhea caused by overgrowth of the bacterium C. difficile)
Studies Link Noroxin and Aortic Aneurysm
Two recent studies have found that fluoroquinolone antibiotics like Noroxin could damage collagen in the aorta, increasing the risk of aneurysm. The first study was published in JAMA Internal Medicine in October 2015.
Researchers in Taiwan looked at data on 1,477 patients who used fluoroquinolones and had an aortic aneurysm between Jan. 2000 and Dec. 2011. They found a 2.4-fold increased risk of the condition within 60 days of initiating treatment, as well as a 50% increased risk associated with prior fluoroquinolone use.
A month after the JAMA study was published, additional research in the British Medical Journal (BMJ) identified a tripled increased risk of aortic aneurysm associated with fluoroquinolone antibiotics. Conclusions were based on data from 650,000 Canadians who took fluoroquinolones between 1997 and 2012, including 1.1% (18,391) who suffered an aortic aneurysm.
Aortic Aneurysm Symptoms
Most aortic aneurysms have no symptoms unless they rupture. If a rupture does occur, symptoms may include:
- Abdominal or back pain
- Pain spreading from the abdomen or back to the pelvis, legs or buttocks
- Clammy or sweaty skin
- Increased heart rate
- Shock or loss of consciousness
Call your doctor right away if you are experiencing any of these symptoms. A ruptured aneurysm can be fatal if not treated in a timely manner.
Fluoroquinolone Tendon Ruptures
In 2008, FDA required that a black box warning be added to the labeling of Noroxin indicating that the drug may increase the risk of tendonitis and tendon ruptures. Patients over the age of 60, those taking corticosteroid medications, and patients who have undergone a transplant are most likely to suffer a rupture, according to the warning. In some cases, tendon problems can occur long after patients quit taking Noroxin.
In August 2013, FDA issued a Drug Safety Communication advising the public that it was requiring a label change for fluoroquinolone antibiotics to “better describe the serious side effect of peripheral neuropathy,” which can occur soon after treatment begins. The condition is associated with oral and injectable fluoroquinolones, but not topical formulations applied to the eyes and ears.
According to the Mayo Clinic, peripheral neuropathy is a result of damage to the peripheral nerves which causes symptoms such as weakness, numbness and pain, typically in the hands and/or feet. Patients with the condition generally describe the pain as stabbing, burning or tingling.
Noroxin Class Action Lawsuit Information
A class action lawsuit is a complaint filed on behalf of a group, or class, of individuals seeking compensation for damages caused by a company. The class typically consists of consumers and/or family members who have been injured or killed by the company’s product.
In some cases, a class action lawsuit may offer some advantages, such as increased efficiency of the legal process, lower costs of litigation and a solution to a common problem wherein small recoveries do not provide the incentive for any individual or law firm to file an individual complaint.
However, class actions can also be disadvantageous to many class members, as they may be forced into a blanket settlements and higher attorney fees. At Schmidt & Clark, LLP, we understand that our clients are suffering emotionally and economically due to their injuries, and we plan to maximize each recovery by filing individual Noroxin lawsuits on their behalf.
Do I Have a Noroxin Lawsuit?
The Class Action Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs in Noroxin lawsuits. We are handling individual litigation nationwide and currently investigating potential settlements in all 50 states.
Free Confidential Case Evaluation: Again, if you were injured by the side effects of Noroxin or other fluoroquinolone antibiotic medication, you should contact our law firm immediately. You may be entitled to compensation by filing a suit and we can help.